Document Detail

Orthodontic treatment of patients medicated with bisphosphonates-a clinical case report.
MedLine Citation:
PMID:  23299652     Owner:  NLM     Status:  Publisher    
INTRODUCTION: Bisphosphonates (BP) are an established medication, e.g., for the prevention/therapy of osteoporosis. The effects of the changed bone metabolism for orthodontic treatments are unknown. CASE REPORT: A 66-year-old woman underwent a total oral rehabilitation. The therapy included (1) tooth extractions, (2) periodontal treatment, (3) insertion of dental implants, (4) provisional implant restorations, (5) orthodontic treatment, and (6) definite implant restorations. The orthodontic tooth movements were in- and retrusion of the upper frontal teeth, intrusion of the lower front teeth, using the dental implants as skeletal anchorage. After implant insertion and one month before beginning the orthodontic treatment, osteoporosis was diagnosed in this patient and, without notification to our facility, BP treatment was initiated by her general practitioner (alendronate oral, 70 mg/week), with an overall duration of intake of 7 months. After 13 months, the orthodontic treatment was successfully accomplished; however enlarged periodontal gaps, sclerotic bone areas, and mild apical root resorptions of the upper frontal teeth were found in this patient. CONCLUSION: Currently, there are no recommendations for orthodontic patients undergoing BP therapy. Orthodontic tooth movement in this low-risk patient with a short duration of intake and a low-dose BP medication was possible. Because of the reduced bone metabolism and the higher amount of side effects, the treatment should be performed with extremely light forces and frequent monitoring.
E Krieger; B d'Hoedt; H Scheller; C Jacobs; C Walter; H Wehrbein
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-10
Journal Detail:
Title:  Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie     Volume:  -     ISSN:  1615-6714     ISO Abbreviation:  J Orofac Orthop     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9713484     Medline TA:  J Orofac Orthop     Country:  -    
Other Details:
Languages:  GER     Pagination:  -     Citation Subset:  -    
Department of Orthodontics, Medical Center of Johannes Gutenberg University Mainz, Augustusplatz 2, 55131, Mainz, Germany,
Vernacular Title:
Kieferorthopädische Behandlung bei Patienten unter Bisphosphonattherapie - ein klinischer Fallbericht.
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