| Orthodeoxia Platypnea Syndrome in a Patient With Lipomatous Hypertrophy of the Interatrial Septum Due to Long-term Steroid Use. | |
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MedLine Citation:
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PMID: 21285060 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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We describe an unusual case of orthodeoxia platypnea syndrome exacerbated by right ventricular inflow obstruction due to iatrogenic steroid-induced adipose deposition in cardiac tissues. A 68-year-old man on long-term prednisone therapy for eosinophilic pneumonia presented with progressive dyspnea worsened by bending forward. By using pulse oximetry, he was noted to have positional hypoxemia. Transthoracic echocardiogram demonstrated normal right-sided pressures but severe right to left shunting through a patent foramen ovale. Transesophageal echocardiogram showed a large patent foramen ovale, severe lipomatous hypertrophy of the interatrial septum, and massive adipose deposition in the pericardium causing compression of the right ventricular inflow tract. The patient underwent percutaneous closure of the patent foramen ovale, which resulted in the resolution of symptoms and hypoxemia. This case is unique because long-term steroid use resulted in reverse Lutembacher physiology and clinical orthodeoxia platypnea syndrome by inducing lipomatous hypertrophy of the interatrial septum and compression of the right atrium. |
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Authors:
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Syed S I Bokhari; Howard J Willens; Maureen H Lowery; Adam Wanner; Eduardo Demarchena |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Chest Volume: 139 ISSN: 1931-3543 ISO Abbreviation: Chest Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-02-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0231335 Medline TA: Chest Country: United States |
Other Details:
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Languages: eng Pagination: 443-5 Citation Subset: AIM; IM |
Affiliation:
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MBBS, c/o Jennifer Mendez, University of Miami, #4062, 1400 NW 12th Ave, Miami, FL 33136. sbokhari@med.miami.edu. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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