Document Detail

Orthanilic acid-promoted reverse turn formation in peptides.
MedLine Citation:
PMID:  23392615     Owner:  NLM     Status:  Publisher    
Orthanilic acid (2-aminobenzenesulfonic acid, (S)Ant), an aromatic β-amino acid, has been shown to be highly useful in inducing a folded conformation in peptides. When incorporated into peptide sequences (Xaa-(S)Ant-Yaa), this rigid aromatic β-amino acid strongly imparts a reverse-turn conformation to the peptide backbone, featuring robust 11-membered-ring hydrogen-bonding.
Sangram S Kale; Gowri Priya; Amol S Kotmale; Rupesh L Gawade; Vedavati G Puranik; P R Rajamohanan; Gangadhar J Sanjayan
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-2-8
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  -     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-2-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Division of Organic Chemistry, National Chemical Laboratory, Dr Homi Bhabha Road, Pune 411 008, India.
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