Document Detail

Oropharyngoesophageal scintigraphy in the diagnostic algorithm of laryngopharyngeal reflux disease: a useful exam?
MedLine Citation:
PMID:  15886624     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the role of oropharyngoesophageal scintigraphy in the diagnostic approach to patients with laryngopharyngeal reflux (LPR). STUDY DESIGN: Forty-one patients with chronic laryngopharyngeal symptoms and a control group of 15 healthy volunteers were examined. All subjects underwent standard oropharyngoesophageal scintigraphy. The following parameters were considered: activity-time curves, presence of double peaks and reduced slope in oropharyngeal phase, presence of accelerated or slowed esophagogastric transit, persistence of radioactive material on the pharyngeal or esophageal mucosa, and presence of gastroesophageal reflux (GER) under exercise. RESULTS: There were objective signs of laryngeal reflux in 80.5% of the patients. In 82.9%, scintigraphy documented several associated morphofunctional pathologic patterns: positive GER test (61.0%), presence of double peaks (36.6%), indirect signs of pharyngoesophageal inflammation (31.7%), hypotonic lower esophageal sphincter (17.1%), and slowed esophageal clearance (9.8%). CONCLUSIONS: Oropharyngoesophageal scintigraphy may be used as preliminary examination in outpatients with signs and symptoms of LPR. Cases of classic gastroesophageal reflux disease could be separated from those of LPR disease and therefore submitted to more invasive instrumental examinations.
Jacopo Galli; Mariangela Volante; Claudio Parrilla; Mario Rigante; Venanzio Valenza
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery     Volume:  132     ISSN:  0194-5998     ISO Abbreviation:  Otolaryngol Head Neck Surg     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-05-11     Completed Date:  2005-06-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508176     Medline TA:  Otolaryngol Head Neck Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  717-21     Citation Subset:  IM    
Department of Otolaryngology, Catholic University of the Sacred Heart, Largo Gemelli n. 8, 00168 Rome, Italy.
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MeSH Terms
Gastroesophageal Reflux / radionuclide imaging
Hypopharynx / radionuclide imaging*
Laryngeal Diseases / radionuclide imaging*
Middle Aged
Pharyngeal Diseases / radionuclide imaging*
Radiation Dosage

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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