Document Detail


Oropharyngeal tularemia--a differential diagnosis of tonsillopharyngitis and cervical lymphadenitis.
MedLine Citation:
PMID:  20213378     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Francisella tularensis, the causative agent of tularemia, has been recognized as a human and zoonotic pathogen for almost 100 years. The increasing number of tularemia outbreaks in regions of Europe outside the classic endemic areas in recent years has prompted renewed interest in this rare infectious disease. We report on a case of oropharyngeal tularemia in an 18-year-old girl from Bavaria (Germany) who presented with tonsillopharyngitis and cervical lymphadenitis. Strongly positive serological tests and PCR detection of F. tularensis subsp. holarctica in lymph node tissue led to the diagnosis of tularemia. After long-term treatment with doxycycline, partly in combination with ciprofloxacin, the patient recovered completely. Clinical presentation, diagnostics, treatment and recent epidemiological aspects of tularemia in Europe are discussed in this case report and review of the literature.
Authors:
Julia Dlugaiczyk; Thomas Harrer; Jochen Zwerina; Maximilian Traxdorf; Stephan Schwarz; Wolf Splettstoesser; Walter Geissd?rfer; Christoph Schoerner
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Wiener klinische Wochenschrift     Volume:  122     ISSN:  1613-7671     ISO Abbreviation:  Wien. Klin. Wochenschr.     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-03-09     Completed Date:  2010-06-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  21620870R     Medline TA:  Wien Klin Wochenschr     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  110-4     Citation Subset:  IM    
Affiliation:
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Erlangen, Germany. julia_dlugaiczyk@yahoo.de
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MeSH Terms
Descriptor/Qualifier:
Diagnosis, Differential
Female
Humans
Mouth Diseases / diagnosis*
Neck
Pharyngeal Diseases / diagnosis*
Pharyngitis / complications,  diagnosis
Tonsillitis / complications,  diagnosis
Tuberculosis, Lymph Node / diagnosis
Tularemia / diagnosis*
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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