Document Detail


Oromucosal midazolam: a guide to its use in paediatric patients with prolonged acute convulsive seizures.
MedLine Citation:
PMID:  22928704     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Oromucosal midazolam (Buccolam™), a benzodiazepine, is approved in the EU for the treatment of paediatric patients (aged 3 months to <18 years) with acute, prolonged, convulsive seizures. In clinical trials in children with prolonged, acute, convulsive seizures, oromucosal midazolam was at least as effective as rectal diazepam and as effective as intravenous diazepam in the treatment of seizures and was generally well tolerated. It has several advantages over rectal diazepam, the previous gold standard of treatment, such as having a more convenient and socially acceptable administration route.
Authors:
Lesley J Scott; Katherine A Lyseng-Williamson; Karly P Garnock-Jones
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  CNS drugs     Volume:  26     ISSN:  1172-7047     ISO Abbreviation:  CNS Drugs     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9431220     Medline TA:  CNS Drugs     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  893-7     Citation Subset:  IM    
Affiliation:
Adis, Auckland, New Zealand.
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