Document Detail

Hyperandrogenism does not predispose patients to photoepilatory treatment failure: a single-center review.
MedLine Citation:
PMID:  20883289     Owner:  NLM     Status:  MEDLINE    
Studies have suggested that patients with PCOS tend to be more treatment resistant to light-mediated depilation compared with their non-PCOS counterparts. We conducted a retrospective assessment of 29 hirsute patients treated between January 2006 and February 2007 to assess whether those with unsatisfactory hair clearance after treatment with intense pulsed light (IPL) were predominantly hyperandrogenic. The number of IPL sessions was also recorded for those patients failing to improve on treatment. Seventy-six percent had satisfactory hair clearance where hyperandrogenic patients dominated. All patients required an average of six treatments before discharge. Eighty-eight percent of poor responders were normoandrogenic. Our hyperandrogenic cohort appeared more responsive to IPL than the normoandrogenic patients. From our observations, the presence of hyperandrogenism does not indicate treatment resistance. This standpoint is unique and warrants a randomized trial directly comparing the two groups to investigate whether a positive or negative relationship actually exists.
Marisa Taylor; Maria Gonzalez
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of cosmetic dermatology     Volume:  9     ISSN:  1473-2165     ISO Abbreviation:  J Cosmet Dermatol     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-10-04     Completed Date:  2011-02-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101130964     Medline TA:  J Cosmet Dermatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  169-73     Citation Subset:  IM    
Copyright Information:
© 2010 Wiley Periodicals, Inc.
Department of Dermatology, School of Medicine, Cardiff University, Cardiff, UK.
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MeSH Terms
Androgens / blood
Follicle Stimulating Hormone / blood
Genetic Predisposition to Disease
Hair Removal / methods*
Hirsutism / therapy*
Hyperandrogenism / complications*,  genetics
Luteinizing Hormone / blood
Middle Aged
Reference Values
Retrospective Studies
Treatment Failure
Young Adult
Reg. No./Substance:
0/Androgens; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone

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