Document Detail


Origin of sex for error repair. II. Rarity and extreme environments.
MedLine Citation:
PMID:  7709369     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a previous paper we studied the simultaneous, and at times conflicting, needs of coping with DNA damage, efficient cell replication, and the avoidance of cell mortality. These selective factors operated on sexual and asexual haploid and diploid populations that were reproductively isolated from one another. We concluded, in part, that a sexual type of cell could not expand from extreme rarity in populations dominated by asexual haploid and diploid cells. In the present paper we show that it is relatively easy for a rare sexual mutant to expand in a population dominated by asexual haploid cells if some matings occur between sexual and asexual cell types. We also study the persistence of sex in high mortality, high damage environments, in which neither the asexual diploid nor haploid can survive. The diploid cannot survive because its lower birth rate cannot overcome mortality and the haploid cannot survive because its birth rate cannot overcome gene damage. Sex can persist in these punishing environments by tuning the parameters of the sexual cycle, and the fusion and splitting rates, into a specified region, thereby reaping both benefits of damage repair and efficient replication.
Authors:
R E Michod; A Long
Related Documents :
3803449 - Prostaglandin binding does not require direct cell-cell contact during chick myogenesis...
6180089 - Isolation of two species of human lymphoblastoid (namalva) cell-derived interferon that...
9135999 - Genetic analysis of default mating behavior in saccharomyces cerevisiae.
2780559 - Cytoplasmic requirement for peroxisome biogenesis in chinese hamster ovary cells.
9151849 - Virus-like particle-induced fusion from without in tissue culture cells: role of outer-...
12960149 - Regulation of progenitor cell fusion by abcb5 p-glycoprotein, a novel human atp-binding...
22897319 - In vitro study of adherence, invasion, and persistence of streptococcus iniae in fibrob...
5413819 - Localization of the beta-glucosidases in neurospora crassa.
7785059 - Peroxisome proliferator-activated receptor response specificities as defined in yeast a...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Theoretical population biology     Volume:  47     ISSN:  0040-5809     ISO Abbreviation:  Theor Popul Biol     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-05-05     Completed Date:  1995-05-05     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0256422     Medline TA:  Theor Popul Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  56-81     Citation Subset:  IM    
Affiliation:
Department of Ecology and Evolutionary Biology, University of Arizona, Tucson 85721.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Cell Division / genetics
Cell Physiological Phenomena
Cell Survival / genetics
DNA Damage / genetics*
DNA Repair / genetics*
DNA Replication / genetics
Diploidy*
Haploidy*
Models, Genetic
Mutation
Reproduction, Asexual / genetics
Sex*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Origin of sex for error repair. I. Sex, diploidy, and haploidy.
Next Document:  Authenticity as a foundational principle of medical ethics.