Document Detail


Origin and differentiation of the endocrine cells of the ovary.
MedLine Citation:
PMID:  3897527     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A large proportion of the somatic cells of the developing ovaries of mouse, human and rabbit stems from the mesonephric tissue. In the immature mouse ovary and in the 19-day-old fetal rabbit ovary, the first steroid-producing cells differentiate among the mesonephric-derived cells within the ovary. In the fetal human ovary, the first steroid-producing cells arise in the inner part of the cortex and differentiate concomitantly with the formation of small follicles. The origin of the early steroid-producing cells in the human ovary is still uncertain. During early ovarian development, formation and further differentiation of the steroid-producing interstitial cells seem to continue only in areas devoid of free viable germ cells.
Authors:
A G Byskov; P E Høyer; L Westergaard
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of reproduction and fertility     Volume:  75     ISSN:  0022-4251     ISO Abbreviation:  J. Reprod. Fertil.     Publication Date:  1985 Sep 
Date Detail:
Created Date:  1985-10-24     Completed Date:  1985-10-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376367     Medline TA:  J Reprod Fertil     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  299-306     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Differentiation
Embryonic and Fetal Development
Female
Humans
Immunoenzyme Techniques
Mesonephros / ultrastructure
Mice
Microscopy, Electron
Oocytes / ultrastructure
Ovary / cytology*,  ultrastructure
Rabbits

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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