Document Detail


Origin of the commonly observed secondary relaxation process in saccharides.
MedLine Citation:
PMID:  20695497     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Broadband dielectric relaxation studies were performed on D-glucose and 1,6-anhydro-D-glucose. In the liquid phase of both systems, one can observe the cluster relaxation and structural relaxation. In the glassy state of D-glucose two secondary relaxations were recorded. The slower one, hardly detectable in the loss spectra, was identified as the Johari-Goldstein type (JG) relaxation. The faster one, the gamma-relaxation, is visible as a well pronounced peak. For the past few years the origin of this process has been a subject of hot debate. Different authors have speculated about the source of this relaxation, but no consensus was reached. Moreover, application of more sophisticated method, such as NMR and MD simulations have not resolved this problem yet. Comparison of the dielectric loss spectra measured for D-glucose and 1,6-anhydro-D-glucose, combined with other experimental findings described in detail in this paper, enabled us to certify unquestionably, that the rotation of hydroxymethyl group is the origin of gamma-relaxation in D-glucose as well as in the whole family of saccharides. Additionally, calculations of conformational changes with use of density functional theory (DFT) were performed to support our identification.
Authors:
K Kaminski; P Wlodarczyk; K Adrjanowicz; E Kaminska; Z Wojnarowska; M Paluch
Related Documents :
4085157 - Coronary and peripheral vascular resistance in the anaesthetized diabetic sheep.
11685657 - Altered gap junction activity in cardiovascular tissues of diabetes.
22012087 - Electrocardiographic signals and swarm-based support vector machine for hypoglycemia de...
11587047 - Follow-up of the who multinational study of vascular disease in diabetes: general descr...
3033857 - Reproducible high yield of rat islets by stationary in vitro digestion following pancre...
6773457 - Spurious serum creatinine elevations in ketoacidosis.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The journal of physical chemistry. B     Volume:  114     ISSN:  1520-5207     ISO Abbreviation:  J Phys Chem B     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-26     Completed Date:  2010-12-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101157530     Medline TA:  J Phys Chem B     Country:  United States    
Other Details:
Languages:  eng     Pagination:  11272-81     Citation Subset:  IM    
Affiliation:
Institute of Physics, Silesian University, ul. Uniwersytecka 4, 40-007 Katowice, Poland. kaminski@us.edu.pl
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Glucose / analogs & derivatives*,  chemistry*
Magnetic Resonance Spectroscopy
Molecular Dynamics Simulation
Chemical
Reg. No./Substance:
498-07-7/1,6-anhydro-beta-glucopyranose; 50-99-7/Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Thermodynamic Origin of Selective Binding of ?-Cyclodextrin Derivatives with Chiral Chromophoric Sub...
Next Document:  Characterization of glycosyltransferase DesVII and its auxiliary partner protein DesVIII in the meth...