| Orientation decoding depends on maps, not columns. | |
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MedLine Citation:
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PMID: 21451017 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The representation of orientation in primary visual cortex (V1) has been examined at a fine spatial scale corresponding to the columnar architecture. We present functional magnetic resonance imaging (fMRI) measurements providing evidence for a topographic map of orientation preference in human V1 at a much coarser scale, in register with the angular-position component of the retinotopic map of V1. This coarse-scale orientation map provides a parsimonious explanation for why multivariate pattern analysis methods succeed in decoding stimulus orientation from fMRI measurements, challenging the widely held assumption that decoding results reflect sampling of spatial irregularities in the fine-scale columnar architecture. Decoding stimulus attributes and cognitive states from fMRI measurements has proven useful for a number of applications, but our results demonstrate that the interpretation cannot assume decoding reflects or exploits columnar organization. |
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Authors:
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Jeremy Freeman; Gijs Joost Brouwer; David J Heeger; Elisha P Merriam |
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Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: The Journal of neuroscience : the official journal of the Society for Neuroscience Volume: 31 ISSN: 1529-2401 ISO Abbreviation: J. Neurosci. Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-03-31 Completed Date: 2011-05-30 Revised Date: 2012-05-07 |
Medline Journal Info:
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Nlm Unique ID: 8102140 Medline TA: J Neurosci Country: United States |
Other Details:
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Languages: eng Pagination: 4792-804 Citation Subset: IM |
Affiliation:
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Center for Neural Science, New York University, New York, New York 10003, USA. freeman@cns.nyu.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Brain Mapping / methods* Female Humans Magnetic Resonance Imaging / methods Male Orientation / physiology* Photic Stimulation / methods* Visual Cortex / physiology* Young Adult |
| Grant Support | |
ID/Acronym/Agency:
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R01 EY016752-04/EY/NEI NIH HHS; R01 EY016752-05/EY/NEI NIH HHS; R01 EY016752-05S1/EY/NEI NIH HHS; R01 NS047493-07/NS/NINDS NIH HHS; R01 NS047493-08/NS/NINDS NIH HHS; R01-EY016752/EY/NEI NIH HHS; R01-NS047493/NS/NINDS NIH HHS |
| Comments/Corrections | |
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