Document Detail

Organophosphorus pesticide residues in Greek virgin olive oil: levels, dietary intake and risk assessment.
MedLine Citation:
PMID:  18636365     Owner:  NLM     Status:  MEDLINE    
The occurrence of organophosphorus pesticide (OPs) and their metabolite residues was investigated in 167 samples of Greek virgin olive oil during a 2-year (2004-2005) sampling campaign. A total of 30.5% of samples contained detectable residues, although only one sample contained dimethoate residues above the maximum residue limit. Among the seven detected OPs, fenthion and fenthion sulfoxide residues were detected in 10.8 and 14.4% of the samples, respectively, at levels of 0.003-0.61 mg kg(-1). Dimethoate was detected in 10.2% of the samples at 0.003-0.057 mg kg(-1). The acute dietary risk assessment was undertaken by determining the national estimated short-term intake (NESTI); for chronic dietary risk assessment, the national theoretical maximum daily intake (NTMDI) and national estimated daily intake (NEDI) were calculated. The estimated intakes (NESTI and NEDI) of each pesticide were <7 and <0.86% of the corresponding acute reference doses (ARfDs) and acceptable daily intakes (ADIs), respectively. A cumulative risk assessment was performed using the hazard index (HI) and toxicity equivalence factor (TEF), taking into account that OPs share the same toxicological mechanism. The determined HI and TEF values were found to represent only a small portion of the respective ADIs or ARfDs. These results indicate that there is neither acute nor chronic risk for the Greek population through olive oil consumption.
C S Tsoutsi; I K Konstantinou; D G Hela
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment     Volume:  25     ISSN:  1944-0057     ISO Abbreviation:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-09-19     Completed Date:  2008-12-05     Revised Date:  2009-08-13    
Medline Journal Info:
Nlm Unique ID:  101485040     Medline TA:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess     Country:  England    
Other Details:
Languages:  eng     Pagination:  1225-36     Citation Subset:  IM    
Department of Chemistry, University of Ioannina, Ioannina 45110, Greece.
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MeSH Terms
Dietary Fats, Unsaturated / administration & dosage
Food Contamination / analysis*
Organophosphorus Compounds / analysis*,  toxicity
Pesticide Residues / analysis*,  toxicity
Pesticides / analysis*,  toxicity
Plant Oils / chemistry*
Proportional Hazards Models
Risk Assessment / methods
Reg. No./Substance:
0/Dietary Fats, Unsaturated; 0/Organophosphorus Compounds; 0/Pesticide Residues; 0/Pesticides; 0/Plant Oils; 8001-25-0/olive oil

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