Document Detail

Organohalogen levels in harbor seal (Phoca vitulina) pups increase with duration of nursing.
MedLine Citation:
PMID:  16020196     Owner:  NLM     Status:  MEDLINE    
Maternal transfer of persistent marine contaminants to offspring via milk has been documented in marine mammals, but temporal dynamics of this phenomenon throughout the lactation period are poorly understood. Exposures to organohalogens were investigated in harbor seal pups admitted to a rehabilitation center in north central California during the lactation periods of 2001 and 2002. Ten congeners of PCBs, three congeners of PBDEs, and p,p'-DDE were quantified in whole blood samples. Levels of contaminants increased with admit date, assumed to correlate positively with pup age. This trend was significant when latitude of stranding site, body condition, and body length were included as variables in the model. Contaminant-admit date relationships appeared nonlinear (i.e., threshold or exponential), with greatest increases in contaminant concentrations during late lactation.
Jennifer C C Neale; Kara R Schmelzer; Frances M D Gulland; Elizabeth A Berg; Ronald S Tjeerdema
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of toxicology and environmental health. Part A     Volume:  68     ISSN:  1528-7394     ISO Abbreviation:  J. Toxicol. Environ. Health Part A     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-07-19     Completed Date:  2005-08-02     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  100960995     Medline TA:  J Toxicol Environ Health A     Country:  England    
Other Details:
Languages:  eng     Pagination:  687-91     Citation Subset:  IM    
Department of Environmental Toxicology, University of California at Davis, Davis, California 95616, USA.
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MeSH Terms
Dichlorodiphenyl Dichloroethylene
Halogenated Diphenyl Ethers
Hydrocarbons, Halogenated / blood*,  metabolism
Milk / chemistry*
Phenyl Ethers
Polybrominated Biphenyls
Polychlorinated Biphenyls
Water Pollutants, Chemical / blood*
Grant Support
5 T32 ES07059-25/ES/NIEHS NIH HHS
Reg. No./Substance:
0/Halogenated Diphenyl Ethers; 0/Hydrocarbons, Halogenated; 0/Insecticides; 0/Phenyl Ethers; 0/Polybrominated Biphenyls; 0/Polychlorinated Biphenyls; 0/Water Pollutants, Chemical; 32534-81-9/pentabromodiphenyl ether; 72-55-9/Dichlorodiphenyl Dichloroethylene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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