| Organohalogen chemicals in human blood from the United Kingdom. | |
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MedLine Citation:
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PMID: 16236409 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Blood serum from 154 volunteers at 13 UK locations in 2003 were analysed for a range of PCBs, organochlorine pesticides and PBDEs. HCB, p,p'-DDE and p,p'-DDT and beta-HCH were the dominant organochlorine pesticides in most samples. BDEs 47, 99, 100, 153, 154 and 183 were the most regularly detected PBDEs. This study is the first report of BDE209 in UK human blood (found in 11 samples, range < 15-240 ng/g lipid). Concentration and age correlated for the less easily metabolised PCBs, p,p'-DDT and p,p'-DDE, HCB and HCHs. With increasing age females tended to have lower concentrations of the more chlorinated PCBs than males. Similar PBDE concentrations, and distributions, to those reported in the general population in Sweden in 2002 were found, despite differences in historical PBDE production and usage. There is increasing regulation to control persistent and bioaccumulative chemicals, and establishing human exposure will help to identify substances which should be urgently phased out. |
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Authors:
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Gareth O Thomas; Matthew Wilkinson; Susan Hodson; Kevin C Jones |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2005-10-19 |
Journal Detail:
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Title: Environmental pollution (Barking, Essex : 1987) Volume: 141 ISSN: 0269-7491 ISO Abbreviation: Environ. Pollut. Publication Date: 2006 May |
Date Detail:
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Created Date: 2006-03-20 Completed Date: 2006-12-07 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 8804476 Medline TA: Environ Pollut Country: England |
Other Details:
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Languages: eng Pagination: 30-41 Citation Subset: IM |
Affiliation:
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Department of Environmental Sciences, IENS, Lancaster University, Lancaster LA1 4YQ, UK. g.o.thomas@lancaster.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Distribution Blood Specimen Collection / methods Environmental Exposure Environmental Monitoring / methods* Environmental Pollutants / blood* Female Flame Retardants / analysis Geography Great Britain Halogenated Diphenyl Ethers Humans Hydrocarbons, Chlorinated / blood Hydrocarbons, Halogenated / blood* Linear Models Male Patient Selection Pesticides / blood* Phenyl Ethers / blood Polybrominated Biphenyls / blood Polychlorinated Biphenyls / blood Sensitivity and Specificity Sex Distribution Sweden United States Urban Population |
| Chemical | |
Reg. No./Substance:
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0/Environmental Pollutants; 0/Flame Retardants; 0/Halogenated Diphenyl Ethers; 0/Hydrocarbons, Chlorinated; 0/Hydrocarbons, Halogenated; 0/Pesticides; 0/Phenyl Ethers; 0/Polybrominated Biphenyls; 0/Polychlorinated Biphenyls; 1163-19-5/decabromobiphenyl ether; 32534-81-9/pentabromodiphenyl ether |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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