Document Detail

Organochlorine pesticides in specimens from women undergoing spontaneous abortion, premature of full-term delivery.
MedLine Citation:
PMID:  7218781     Owner:  NLM     Status:  MEDLINE    
Organochlorine insecticides (BHC, aldrin, p,p'-DDE, p,p'-DDD, p,p'-DDT) were measured in the blood, placenta and fetus of women experiencing spontaneous abortions, preterm labor or full-term labor using an electron-capture gas chromatographic method. The following trend was found for insecticide concentrations in each of the specimens tested: spontaneous abortions greater than preterm greater than full-term. One conclusion of this work is that the organochlorine insecticides act as antagonists to pregnancy. A plausible explanation for the facilitory role of organochlorine insecticides in the initiation of preterm labor/abortion is hypothesized.
M C Saxena; M K Siddiqui; T D Seth; C R Krishna Murti; A K Bhargava; D Kutty
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of analytical toxicology     Volume:  5     ISSN:  0146-4760     ISO Abbreviation:  J Anal Toxicol     Publication Date:    1981 Jan-Feb
Date Detail:
Created Date:  1981-06-23     Completed Date:  1981-06-23     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7705085     Medline TA:  J Anal Toxicol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  6-9     Citation Subset:  IM    
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MeSH Terms
Abortion, Spontaneous / metabolism*
Fetus / metabolism
Hydrocarbons, Chlorinated*
Insecticides / analysis*
Labor, Obstetric
Obstetric Labor, Premature / metabolism*
Pesticide Residues / analysis
Placenta / metabolism
Reg. No./Substance:
0/Hydrocarbons, Chlorinated; 0/Insecticides; 0/Pesticide Residues

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