Document Detail

Organochlorine pesticide residues in biological compartments of healthy mothers.
MedLine Citation:
PMID:  22368179     Owner:  NLM     Status:  Publisher    
The present study was conducted to detect placental and breast milk (BM) transfer of organochlorine pesticides (OCPs) between biological compartments in healthy lactating mothers. The study explores the effect of parity, breast-feeding and urban/rural residence on body burden of OCP residues. The study included 38 healthy participants submitted to cesarean delivery. Sociodemographic data and specimens of maternal and umbilical sera, adipose tissue (Adp T) and BM were collected. Specimens were analyzed to detect OCP residues. The lindane in BM, o,p'-dichlorodiphenyldichloroethane (DDD) in maternal serum (MS) and total dichlorodiphenyltrichloroethane (DDT) and o,p'-dichlorodiphenyldichloroethylene in umbilical serum were the only detected residues in significantly higher frequencies and/or means in the primigravidae than multigravidae. There was a high risk of detecting o,p'-DDD (odds ratio = 8.3) in umbilical serum of the mothers with o,p'-DDD detected in the MS. Total DDT was detected in about 65% of specimens of BM, MS and Adp T and in about 40% of the umbilical serum specimens. There was only a significant positive correlation between total DDT residues in the BM and Adp T. Total DDT residues in umbilical serum and Adp T were significantly higher in the urban than in the rural mothers. The detection of some OCPs in maternal biological compartments suggests their potential placental and BM transfer to her child during pregnancy and lactation, respectively. Furthermore, it might reflect the persistence or recent use of these pesticides in the environment.
Safaa Elserougy; Safia Beshir; Amal Saad-Hussein; Assem Abouarab
Related Documents :
8285199 - Frequency and outcome of pregnancy in women on dialysis.
22746289 - Lower circulation levels and activity of alpha-1 antitrypsin in pregnant women with sev...
12448669 - The process of preventing pregnancy: women's experiences and emergency contraception use.
2214099 - Effects of medicaid eligibility expansion on prenatal care and pregnancy outcome in ten...
15370199 - A nova vida: the commoditization of reproduction in central mozambique.
7976239 - Equality in health and health care during pregnancy. a prospective population-based stu...
22223909 - Anaesthetic management for emergency caesarean section in a patient with an untreated r...
17437959 - First trimester maternal serum ischaemia-modified albumin: a marker of hypoxia-ischaemi...
2129779 - Anti-thyroid peroxidase antibodies during pregnancy and postpartum. relation to postpar...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-24
Journal Detail:
Title:  Toxicology and industrial health     Volume:  -     ISSN:  1477-0393     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-2-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8602702     Medline TA:  Toxicol Ind Health     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Environmental and Occupational Medicine, National Research Center, Cairo, Egypt.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The channel capacity of a diagnostic test as a function of test sensitivity and test specificity.
Next Document:  Characterization of species-specific repeats in 613 prokaryotic species.