Document Detail

Organochlorine pesticide contaminations in human milk samples from women living in Amman, Jordan.
MedLine Citation:
PMID:  1514844     Owner:  NLM     Status:  MEDLINE    
Concentration of 15 organochlorine pesticides were determined by capillary gas chromatography in 59 human milk samples collected from the general population during 1989/1990 in the Jordanian capital of Amman. In addition to hexachlorbenzene (HCB), three groups of organochlorine compounds namely, DDT and its metabolites, hexachlorcyclohexane (HCH-isomers) and the cyclopentadiene group (aldrin, dieldrin, endrin, heptachlor, and heptachlor epoxide) were analyzed. The results show that almost all samples contained HCB, beta-HCH, p,p'-DDE and p,p'-DDT, whereas p,p'-DDD, heptachlor, alpha-HCH, gamma-HCH and o,p'DDT were found in 42, 40, 33, 22 and 20 analyzed samples, respectively. The concentration of HCB, beta-HCH, p,p'-DDE, p,p'-DDT and heptachlor expressed on a milk-fat basis (median in mg/kg milk fat): 0.29, 0.4, 2.04, and 0.7 respectively. For the comparative purposes and in order to try to find the possible sources of mother-milk contaminations, different types of locally produced and imported cow milk samples were also analyzed for the same organochlorine compounds. Almost all types of tested milk were contaminated with p,p'-DDE.
Milk samples from 15 women from Amman, Jordan, were analyzed by gas chromatography for 15 chlorinated pesticides including hexachlorobenzene (HCB), DDT, hexachlorocyclohexane (HCH), and several cyclopentadienes and their metabolites. The subjects were a convenience sample aged 19-40, of parity 1-10. Only 3 admitted to pesticide exposure. Almost all samples contained HCB, HCH, and DDT or its isomers. The DDT compound p,p'-DDE was found in the highest concentrations in all samples. The isomers p, p'-DDD, heptachlor, alpha-HCH, gamma-HCH, and o,p'-DDT occurred in 42, 40, 33, 22, and 20 of the samples. (3 or 4 samples were taken from each woman.) Few contained any cyclopentadienes such as aldrin, dieldrin, or endrin. Various dairy milk sources from Jordan were shown to contain HCB, alpha-HCH, gamma-HCH, p,p'-DDT, and p,p'-DDE. Human milk had levels of p,p'-DDE approximately 10 times higher than did local cow's milk. It was estimated that a newborn infant of 3.5 kg would ingest about 0.175 mg of total organochlorine compounds in Jordan.
M A Alawi; N Ammari; Y al-Shuraiki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of environmental contamination and toxicology     Volume:  23     ISSN:  0090-4341     ISO Abbreviation:  Arch. Environ. Contam. Toxicol.     Publication Date:  1992 Aug 
Date Detail:
Created Date:  1992-09-25     Completed Date:  1992-09-25     Revised Date:  2004-11-18    
Medline Journal Info:
Nlm Unique ID:  0357245     Medline TA:  Arch Environ Contam Toxicol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  235-9     Citation Subset:  IM; J    
University of Jordan, Amman.
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MeSH Terms
Chromatography, Gas
Hydrocarbons, Chlorinated*
Insecticides / analysis*
Milk, Human / chemistry*
Reg. No./Substance:
0/Hydrocarbons, Chlorinated; 0/Insecticides

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