Document Detail


Organizing pneumonia in recipients of hematopoietic stem cell transplantation: CT features in 16 patients.
MedLine Citation:
PMID:  22805673     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To evaluate computed tomographic (CT) scans of patients with organizing pneumonia (OP) complicating hematopoietic stem cell transplantation (HSCT).
MATERIALS AND METHODS: A review of patients who underwent HSCT at our institution identified 16 patients who had documented OP on biopsy. Computed tomographic scans were reviewed by 2 thoracic radiologists.
RESULTS: Ground glass opacities (GGO) were seen in 15 patients, consolidation in 8 patients, linear opacities in 8 patients, traction bronchiectasis in 2 patients, and septal thickening in 2 patients. Ground glass opacity was the dominant abnormality in 7 patients, consolidation in 4 patients, and linear opacities in 5 patients. Peribronchovascular distribution was found in 4 patients, peripheral in 2 patients, diffuse in 3 patients; upper lung predominance was found in 10 patients, and lower lung predominance in 5 patients.
CONCLUSION: The principal computed tomographic features of OP after HSCT are ground glass opacities, consolidation and linear opacities, with upper lung predominance. Allowing for a possible sampling bias, these findings differ from those reported in cryptogenic OP and OP from other causes.
Authors:
Sudhakar N J Pipavath; Jonathan H Chung; Jason W Chien; J David Godwin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of computer assisted tomography     Volume:  36     ISSN:  1532-3145     ISO Abbreviation:  J Comput Assist Tomogr     Publication Date:    2012 Jul-Aug
Date Detail:
Created Date:  2012-07-18     Completed Date:  2012-09-25     Revised Date:  2013-07-18    
Medline Journal Info:
Nlm Unique ID:  7703942     Medline TA:  J Comput Assist Tomogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  431-6     Citation Subset:  IM    
Affiliation:
Department of Radiology, University of Washington, Seattle, WA, USA. snjp@u.washington.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Cryptogenic Organizing Pneumonia / radiography*
Female
Hematopoietic Stem Cell Transplantation*
Humans
Male
Middle Aged
Retrospective Studies
Tomography, X-Ray Computed*
Grant Support
ID/Acronym/Agency:
R01 HL090342/HL/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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