Document Detail


Organization, barrier function and antimicrobial lipids of the oral mucosa.
MedLine Citation:
PMID:  23320785     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
As one moves from the skin across the vermilion region of the lip and into the oral cavity the oral mucosa is encountered. The oral mucosa consists of connective tissue known as the lamina propria covered by a stratified squamous epithelium. In the regions of the hard palate and gingiva the epithelium is keratinized like the epidermis. In the buccal region, the floor of the mouth and the underside of the tongue the epithelium is nonkeratinized. The epithelium on the dorsum of the tongue is a specialized epithelium but can be approximated as a mosaic of keratinized and nonkeratinized epithelia. The nonkeratinized epithelial regions do not produce a stratum corneum. Nuclei with intact DNA are retained in the superficial cells. In all regions the outer portions of the epithelium provides a protective permeability barrier, which varies regionally. Antimicrobial lipids at the surfaces of the oral mucosa are an integral part of innate immunity. © 2013 Society of Cosmetic Scientists and the Société Française de Cosmétologie.
Authors:
Deborah V Dawson; David R Drake; Jennifer R Hill; Kim A Brogden; Carol L Fischer; Philip W Wertz
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-16
Journal Detail:
Title:  International journal of cosmetic science     Volume:  -     ISSN:  1468-2494     ISO Abbreviation:  Int J Cosmet Sci     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8007161     Medline TA:  Int J Cosmet Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2013 Society of Cosmetic Scientists and the Société Française de Cosmétologie.
Affiliation:
University of Iowa, Iowa City, IA, 52242.
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