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Organ-specific responses to circulatory disturbances in heart failure: new insights.
MedLine Citation:
PMID:  22432559     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Recent studies have provided new insights into the pathophysiology of congestive heart failure. Organ-specific responses to circulatory disturbances may differ via a hypoperfusion state and a venous congestion state. The liver and the kidneys serve as a good example of a differential injury pattern based on the predominant circulatory insult. Cardiorenal syndrome appears to be a kidney-specific response to predominantly right-sided backward heart failure ("congestive state"), rather than forward heart failure. Despite significant progress in our understanding of cardiorenal interactions, there is no specific therapy for the cardiorenal syndrome, which is a marker of the severity of the heart failure state. ©2011 Wiley Periodicals, Inc.
Authors:
Edgar Argulian; Craig McPherson; Marrick Kukin
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Publication Detail:
Type:  Journal Article     Date:  2011-10-03
Journal Detail:
Title:  Congestive heart failure (Greenwich, Conn.)     Volume:  18     ISSN:  1751-7133     ISO Abbreviation:  Congest Heart Fail     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-03-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9714174     Medline TA:  Congest Heart Fail     Country:  United States    
Other Details:
Languages:  eng     Pagination:  127-31     Citation Subset:  IM    
Copyright Information:
© 2011 Wiley Periodicals, Inc.
Affiliation:
From the Division of Cardiology, St. Luke's - Roosevelt Hospital Center, Columbia University College of Physicians & Surgeons, New York, NY;the Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT.
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