| Organ removal and disappearance half-time of synthetic human pancreatic polypeptide. | |
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MedLine Citation:
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PMID: 7160551 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Human pancreatic polypeptide (HPP) was infused into 6 anesthetized dogs at a constant dose of 1.0 micrograms/kg/h over 60 min. Blood samples for RIA of pancreatic polypeptide were taken repeatedly from a carotid artery, jugular vein, femoral vein, renal vein and mesenteric vein. The calculated tissue removal of HPP in a single passage through these four vascular beds ranged from 24 to 40% and did not differ significantly among them. Mean disappearance half-time on stopping the infusion was 4.5 +/- 0,8 min. The results indicate that HPP is removed at all of the capillary beds tested. |
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Authors:
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J S Swierczek; W Pawlik; S J Konturek; P Gustaw; M Dobrzańska; W Bielański; D H Coy |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Digestion Volume: 25 ISSN: 0012-2823 ISO Abbreviation: Digestion Publication Date: 1982 |
Date Detail:
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Created Date: 1983-04-07 Completed Date: 1983-04-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0150472 Medline TA: Digestion Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 197-200 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Dogs Half-Life Humans Kinetics Pancreatic Polypeptide / blood, metabolism* Radioimmunoassay |
| Chemical | |
Reg. No./Substance:
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59763-91-6/Pancreatic Polypeptide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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