Document Detail

Orexin a elicits arousal electroencephalography without sympathetic cardiovascular activation in isoflurane-anesthetized rats.
MedLine Citation:
PMID:  14633539     Owner:  NLM     Status:  MEDLINE    
IMPLICATIONS: The novel neuropeptides orexins induce arousal associated with activation of the sympathetic nervous system in conscious rats. It is not known whether orexins affect the electroencephalogram (EEG), autonomic nerve activity, or both under anesthesia. Orexin A induced EEG arousal without sympathetic cardiovascular activation in the isoflurane-anesthetized rat. Orexin A might influence the depth of anesthesia.
Yoshikazu Yasuda; Akiko Takeda; Satoru Fukuda; Hisato Suzuki; Masayuki Ishimoto; Yoshiteru Mori; Hirotake Eguchi; Ritsuko Saitoh; Hideyoshi Fujihara; Kazumasa Honda; Takashi Higuchi
Related Documents :
18763079 - Ectopic discharges trigger sympathetic sprouting in rat dorsal root ganglia following p...
7282289 - Variations in the axon reaction in animals of different ages. a light microscopic study...
21670219 - Disposition and metabolism of ticagrelor, a novel p2y12 receptor antagonist, in mice, r...
3938169 - Application of avidin-biotinized peroxidase (abc) method for immunocytochemical localiz...
11677719 - Role of cholinergic mossy fibers in vestibular nuclei in the development of vestibular ...
14985829 - Reduced nitric oxide in the rostral ventrolateral medulla enhances cardiac sympathetic ...
11799139 - Dietary l-carnitine stimulates carnitine acyltransferases in the liver of aged rats.
9623669 - Intravenous injection of guanylin induces mucus secretion from goblet cells in rat duod...
6281819 - In utero taste/odor aversion conditioning in the rat.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  97     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2003-11-24     Completed Date:  2003-12-17     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1663-6     Citation Subset:  AIM; IM    
Departments of Anesthesiology & Reanimatology and. Physiology, Fukui Medical University, Fukui, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anesthesia, Inhalation*
Anesthetics, Inhalation*
Arousal / drug effects*
Blood Pressure / drug effects
Carrier Proteins / administration & dosage,  pharmacology*
Electrocardiography / drug effects
Electroencephalography / drug effects*
Heart Rate / drug effects
Hemodynamics / drug effects*
Injections, Intraventricular
Intracellular Signaling Peptides and Proteins*
Neuropeptides / administration & dosage,  pharmacology*
Rats, Wistar
Sympathetic Nervous System / drug effects*
Reg. No./Substance:
0/Anesthetics, Inhalation; 0/Carrier Proteins; 0/Intracellular Signaling Peptides and Proteins; 0/Neuropeptides; 0/orexins; 26675-46-7/Isoflurane

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Preoperative fentanyl infusion with pharmacokinetic simulation for anesthetic and perioperative mana...
Next Document:  The effect of cerebral monitoring on recovery after general anesthesia: a comparison of the auditory...