Document Detail

Orbitofacial cleft number 5: radiographic, anatomical, and histologic study of a 24-week-old fetus.
MedLine Citation:
PMID:  17102725     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Orbitofacial clefts are caused by a congenital absence of midfacial tissues between the eye and the upper lip just medial to the corner of the mouth. As a whole, facial clefts occur with an incidence of 1.43 to 4.85 per 100,000 births. The exact incidence of these unusual orbital facial clefts is unknown. Only a few clinical cases and their treatment have been reported in the world literature, and no anatomical or histologic study has been presented.
METHODS: The authors present a detailed anatomical and histologic study in a 24-week-old fetus with a right-side no. 5 orbitofacial cleft (according to Tessier's classification).
RESULTS: During the anatomical dissection, it was observed that in the trigeminal Gasser ganglion on the right side there was no infraorbital branch of this nerve. Both the foramen rotundum and the infraorbital groove, where the nerve exits, were hypotrophic.
CONCLUSION: After embryologic analysis of their observation, the authors propose that the orbitofacial no. 5 cleft should be considered as a tissular disruption of the face secondary to damage of the terminal branches of the maxillary nerve.
Claudio Cannistrà; Claire Bontemps; Rodrigo Valero; Giorgio Iannetti; J Patrick Barbet
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Plastic and reconstructive surgery     Volume:  118     ISSN:  1529-4242     ISO Abbreviation:  Plast. Reconstr. Surg.     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-11-14     Completed Date:  2006-11-30     Revised Date:  2014-10-13    
Medline Journal Info:
Nlm Unique ID:  1306050     Medline TA:  Plast Reconstr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1538-42     Citation Subset:  AIM; IM    
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MeSH Terms
Abnormalities, Multiple / pathology*,  radiography*
Face / abnormalities*,  pathology,  radiography*
Fetus / abnormalities*,  pathology,  radiography*
Gestational Age
Orbit / abnormalities*,  pathology,  radiography*

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