| Orbital eosinophilic angiocentric fibrosis case report and review of the literature. | |
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MedLine Citation:
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PMID: 16324746 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To report a patient with a rare case of orbital eosinophilic angiocentric fibrosis (EAF) and to review the literature. DESIGN: Interventional case report. METHODS: A 61-year-old man presented with a 6-week history of right periorbital edema and painless proptosis. Examination revealed a nonaxial proptosis, lateral globe displacement, and mild limitation in right eye adduction. MAIN OUTCOME MEASURES: Clinical course and radiological and histological findings. RESULTS: Orbital imaging revealed a right medial orbital mass with involvement of middle ethmoidal air cells. An orbital biopsy of the mass demonstrated an inflammatory infiltrate with a marked eosinophilic component, onion skinning of vessels, and surrounding fibrosis. The diagnosis of orbital EAF was made. There was no response to a 3-month treatment course with systemic steroids, but the patient did not want any further surgical interventions. CONCLUSION: Although orbital EAF is rare, ophthalmologists need to be aware of this entity, as it may invade the orbit from the sinonasal tract or present as a localized orbital mass. The presence of even minimal sinus involvement and the characteristic histopathology are useful in establishing the correct diagnosis. |
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Authors:
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Igal Leibovitch; Craig L James; Peter J Wormald; Dinesh Selva |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2005-12-01 |
Journal Detail:
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Title: Ophthalmology Volume: 113 ISSN: 1549-4713 ISO Abbreviation: Ophthalmology Publication Date: 2006 Jan |
Date Detail:
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Created Date: 2006-01-03 Completed Date: 2006-01-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7802443 Medline TA: Ophthalmology Country: United States |
Other Details:
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Languages: eng Pagination: 148-52 Citation Subset: IM |
Affiliation:
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Oculoplastic and Orbital Unit, Department of Ophthalmology and Visual Sciences, University of Adelaide, Adelaide, SA, Australia. leiboigal5@yahoo.com.au |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Eosinophilic Granuloma
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drug therapy,
pathology*,
radiography Eosinophils / pathology* Fibrosis Glucocorticoids / therapeutic use Humans Magnetic Resonance Imaging Male Middle Aged Orbital Diseases / drug therapy, pathology*, radiography Prednisolone / therapeutic use Tomography, X-Ray Computed |
| Chemical | |
Reg. No./Substance:
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0/Glucocorticoids; 50-24-8/Prednisolone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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