Document Detail

Orbital decompression for preservation of vision in Graves' ophthalmopathy.
MedLine Citation:
PMID:  8427689     Owner:  NLM     Status:  MEDLINE    
Graves' ophthalmopathy (thyroid eye disease) can result in progressive visual loss. The University of Washington (Seattle) experience in orbital decompression was reviewed for the years 1983 through 1990 to determine overall safety and outcome. Twenty patients underwent transantral decompression of 36 orbits for either steroid therapy failure, steroid therapy intolerance, or recurrence of optic neuropathy with tapering of the steroid therapy. Decompression successfully improved visual function in 33 of the orbits (92%) and a second decompression procedure was successful in another two (5%) of the orbits (6%). There were no major complications or cases of decreased visual function. Diplopia, present preoperatively in 17 patients (85%), was improved in eight patients (47%) and unchanged in nine patients (53%). However, of the three patients without preoperative diplopia (15%), one had development of new-onset diplopia postoperatively. Transantral decompression of the orbit offers a safe and effective therapeutic modality for vision-threatening Graves' ophthalmopathy.
D A Girod; J C Orcutt; C W Cummings
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of otolaryngology--head & neck surgery     Volume:  119     ISSN:  0886-4470     ISO Abbreviation:  Arch. Otolaryngol. Head Neck Surg.     Publication Date:  1993 Feb 
Date Detail:
Created Date:  1993-03-05     Completed Date:  1993-03-05     Revised Date:  2006-03-28    
Medline Journal Info:
Nlm Unique ID:  8603209     Medline TA:  Arch Otolaryngol Head Neck Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  229-33     Citation Subset:  AIM; IM    
Department of Otolaryngology, Head and Neck Surgery, University of Washington, Seattle 98195.
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MeSH Terms
Adrenal Cortex Hormones / adverse effects,  therapeutic use
Aged, 80 and over
Graves Disease / classification,  complications,  surgery*
Hospitals, University
Intraocular Pressure
Least-Squares Analysis
Middle Aged
Orbital Diseases / classification,  complications,  surgery*
Outpatient Clinics, Hospital
Postoperative Complications / epidemiology,  etiology
Retrospective Studies
Severity of Illness Index
Treatment Outcome
Vision Disorders / diagnosis,  etiology
Visual Acuity
Washington / epidemiology
Reg. No./Substance:
0/Adrenal Cortex Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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