| Oral tuberculosis: a clinical evaluation of 42 cases. | |
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MedLine Citation:
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PMID: 10673784 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: A retrospective review of a large series of oro-facial cases of tuberculosis to analyse clinical, histopathological, and radiological aspects, as well as those of chemotherapy. MATERIALS AND METHODS: A total of 42 cases of tuberculosis of the oro-facial region were examined. Thirteen patients had a primary form and 29 a secondary form of the disease. Diagnosis was based on careful clinical examination, Mantoux reaction, histopathological examination, microbiological cultures and immunological investigation with the detection of antibodies against Mycobacteria in the patients' serum (ELISA). RESULTS: Cases examined consisted of 27 males and 15 females. The age range was 3 to 73 years (mean age 31 years). Clinical manifestations comprised oral ulcers in 69.1%, bone involvement in 21.4%, and salivary gland and/or lymph node involvement in 14.3%. A total of 79.4% patients with secondary disease had pulmonary lesions, 15 of whom showed clinical and radiological signs of activity; there was one case of bilateral renal lesions and two of skin lesions. CONCLUSIONS: Oro-facial tuberculosis is often difficult to diagnose and it should be an important consideration in the differential diagnosis of lesions that appear in the oral cavity. The most important diagnostic tools remain a careful clinical evaluation, biopsy for histologic study, as well as acid-fast stains, culture, and immunological assays, and skin testing. |
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Authors:
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M D Mignogna; L L Muzio; G Favia; E Ruoppo; G Sammartino; C Zarrelli; E Bucci |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Oral diseases Volume: 6 ISSN: 1354-523X ISO Abbreviation: Oral Dis Publication Date: 2000 Jan |
Date Detail:
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Created Date: 2001-01-29 Completed Date: 2001-02-15 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9508565 Medline TA: Oral Dis Country: England |
Other Details:
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Languages: eng Pagination: 25-30 Citation Subset: D |
Affiliation:
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Division of Oral Medicine, Faculty of Medicine, University Federico II, Naples, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Antibodies, Bacterial / blood Biopsy Child Child, Preschool Diagnosis, Differential Enzyme-Linked Immunosorbent Assay Female Humans Jaw Diseases / microbiology Male Middle Aged Mycobacterium tuberculosis / growth & development, immunology Oral Ulcer / microbiology Physical Examination Retrospective Studies Salivary Gland Diseases / microbiology Tuberculin Test Tuberculosis, Cutaneous / diagnosis Tuberculosis, Lymph Node / diagnosis Tuberculosis, Oral / diagnosis* Tuberculosis, Osteoarticular / diagnosis Tuberculosis, Pulmonary / diagnosis Tuberculosis, Renal / diagnosis |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Bacterial |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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