| Oral tegafur in the treatment of metastatic breast cancer: a phase II study. | |
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MedLine Citation:
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PMID: 8484979 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Between February 1985 and October 1989, 26 patients previously treated for metastatic breast cancer received oral tegafur, at a median daily dose of 1200 mg. Of these, 21 were evaluable for response. The overall response rate was 29%; six (two in lungs, two in skin and two in lymph nodes) of 44 evaluable lesions (14%) responded to therapy. Haematological toxicity was mild, and no other dose-limiting toxicity was seen. The data indicate some activity in heavily pretreated metastatic breast cancer even after previous 5-FU therapy. |
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Authors:
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M J Kajanti; S O Pyrhönen; A G Maiche |
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Publication Detail:
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Type: Clinical Trial; Clinical Trial, Phase II; Journal Article |
Journal Detail:
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Title: European journal of cancer (Oxford, England : 1990) Volume: 29A ISSN: 0959-8049 ISO Abbreviation: Eur. J. Cancer Publication Date: 1993 |
Date Detail:
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Created Date: 1993-06-07 Completed Date: 1993-06-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9005373 Medline TA: Eur J Cancer Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 863-6 Citation Subset: IM |
Affiliation:
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Department of Radiotherapy and Oncology, Helsinki University Central Hospital, Finland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Adult Aged Blood Cell Count Bone Neoplasms / secondary Breast Neoplasms / blood, drug therapy* Female Humans Lung Neoplasms / secondary Lymphatic Metastasis Middle Aged Skin Neoplasms / secondary Tegafur / administration & dosage, therapeutic use* |
| Chemical | |
Reg. No./Substance:
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17902-23-7/Tegafur |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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