Document Detail

Oral submucous fibrosis--treatment with hyalase.
MedLine Citation:
PMID:  3968475     Owner:  NLM     Status:  MEDLINE    
Oral Submucous Fibrosis (OSMF) is a disease of unknown etiology. A total of 96 patients with Oral Submucous Fibrosis have received four regimens of treatment--local dexamethasone, local hyaluronidase, local combination of dexamethasone and hyaluronidase, and local placental extract. The patients were followed up for a period varying from 3 months to 2 years. The group of patients receiving hyaluronidase alone showed quicker improvement in symptoms although its combination with dexamethasone gave somewhat better longer-term results. A new regimen for the treatment of submucous fibrosis is recommended.
P K Kakar; R K Puri; V P Venkatachalam
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of laryngology and otology     Volume:  99     ISSN:  0022-2151     ISO Abbreviation:  J Laryngol Otol     Publication Date:  1985 Jan 
Date Detail:
Created Date:  1985-03-19     Completed Date:  1985-03-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8706896     Medline TA:  J Laryngol Otol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  57-9     Citation Subset:  AIM; IM    
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MeSH Terms
Dexamethasone / administration & dosage,  therapeutic use*
Drug Therapy, Combination
Hyaluronoglucosaminidase / administration & dosage,  therapeutic use*
Mouth Diseases / drug therapy*
Oral Submucous Fibrosis / drug therapy*
Placental Extracts / therapeutic use
Random Allocation
Time Factors
Reg. No./Substance:
0/Placental Extracts; 50-02-2/Dexamethasone; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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