Document Detail

Oral submucous fibrosis in India: a new epidemic?
MedLine Citation:
PMID:  9707699     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Oral submucous fibrosis (OSF) is a precancerous condition caused by use of the areca nut. The reported prevalence of OSF in Bhavnagar district during 1967 was 0.16%. We investigated whether the impression of an increase in the incidence of the disease was real. METHODS: A house-to-house survey was conducted in Bhavnagar district, Gujarat state. The use of areca nut-containing products and tobacco was assessed through an interviewer administered questionnaire. The oral examination was done by dentists. The diagnostic criteria for OSF was the presence of palpable fibrous bands. RESULTS: A total of 11,262 men and 10,590 women aged 15 years and older were interviewed for their tobacco habits. Among 5018 men who reported the use of tobacco or areca nut, 164 were diagnosed as suffering from OSF. All but four cases were diagnosed among 1786 current areca nut users (age-adjusted relative risk: 60.6). Areca nut was used mostly in mawa, a mixture of tobacco, lime and areca nut, and 10.9% of mawa users had OSF (age-adjusted relative risk: 75.6). The disease as well as areca nut use was concentrated (about 85%) in the lower (< 35 years) age group. CONCLUSIONS: An increase in the prevalence of OSF, especially in the lower age groups, directly attributable to the use of areca nut products was observed. This could lead to an increase in the incidence of oral cancer in the future.
P C Gupta; P N Sinor; R B Bhonsle; V S Pawar; H C Mehta
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The National medical journal of India     Volume:  11     ISSN:  0970-258X     ISO Abbreviation:  Natl Med J India     Publication Date:    1998 May-Jun
Date Detail:
Created Date:  1998-09-23     Completed Date:  1998-09-23     Revised Date:  2009-07-30    
Medline Journal Info:
Nlm Unique ID:  8809315     Medline TA:  Natl Med J India     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  113-6     Citation Subset:  IM    
Tata Institute of Fundamental Research, Maharashatra, India.
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MeSH Terms
India / epidemiology
Middle Aged
Oral Submucous Fibrosis / epidemiology*,  etiology
Plants, Medicinal*
Plants, Toxic
Precancerous Conditions / epidemiology,  etiology
Risk Factors
Smoking / adverse effects
Tobacco, Smokeless / adverse effects

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