Document Detail


Oral and sublingual immunotherapy for food allergy: current progress and future directions.
MedLine Citation:
PMID:  23972904     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Food allergies are increasing in prevalence and present an emerging epidemic for westernized countries. Strict dietary avoidance is the only approved management for food allergy, but accidental exposures regularly occur, leading to significant patient anxiety and decreased quality of life. Over the past decade, oral and sublingual immunotherapies have emerged as potential treatments for food allergy. While several small clinical trials have demonstrated that immunotherapy can desensitize food-allergic individuals, strategies for further enhancing safety and definitively establishing long-term efficacy are needed. This review presents an overview of recent oral and sublingual immunotherapy trials, and provides a glimpse into what the next generation of food immunotherapy may entail.
Authors:
Timothy P Moran; Brian P Vickery; A Wesley Burks
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-8-20
Journal Detail:
Title:  Current opinion in immunology     Volume:  -     ISSN:  1879-0372     ISO Abbreviation:  Curr. Opin. Immunol.     Publication Date:  2013 Aug 
Date Detail:
Created Date:  2013-8-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8900118     Medline TA:  Curr Opin Immunol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013. Published by Elsevier Ltd.
Affiliation:
Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, NC 27710, United States.
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