Document Detail

Oral squamous cell carcinoma metastasizing to the skull bone: a case report and literature review.
MedLine Citation:
PMID:  24598498     Owner:  NLM     Status:  In-Data-Review    
Oral squamous cell carcinoma (SCC) is considered a primarily localized disease, and distant metastasis is not common. An increasing number of case reports involving unusual sites for distant metastasis from oral carcinoma have been reported in the literature. This is likely due to the improved control of cancer at the primary site, increasing the chance of developing a delayed metastasis. This article presents a case of a 58-year-old woman who refused surgical treatment for a very aggressive SCC on the mandibular alveolar ridge. The tumor did not respond to chemotherapy or radiotherapy, and the patient developed metastasis in the skull bone approximately 1 year after the initial diagnosis. The site of the primary tumor (next to the bone) as well as the patient's refusal of the proposed treatment, may have led to the hematological spread of the malignant cells, resulting in the distant metastasis.
Ademar Takahama; Marecelo Brum Correa; Oseli Paes de Almeida; Marcio Ajudarte Lopes
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  General dentistry     Volume:  62     ISSN:  0363-6771     ISO Abbreviation:  Gen Dent     Publication Date:    2014 Mar-Apr
Date Detail:
Created Date:  2014-03-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7610466     Medline TA:  Gen Dent     Country:  United States    
Other Details:
Languages:  eng     Pagination:  59-61     Citation Subset:  D    
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