Document Detail

Oral squamous cell carcinoma associated with khat chewing.
MedLine Citation:
PMID:  17482851     Owner:  NLM     Status:  MEDLINE    
The incidence of oral squamous cell carcinoma has been long associated with smoking, alcohol, and betel quid/areca nut chewing. This article presents a case of a 42-year-old female patient with squamous cell carcinoma of the floor of the mouth, associated with khat chewing. This relatively early presentation of oral squamous cell carcinoma may be linked to the synergistic effect of khat chewing and other known carcinogens such as polycyclic aromatic hydrocarbons and nitrosamines such as 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone, 4-(N-methyl-N-nitrosamino)-4-(3-pyridyl)-1-butanal. With the changing demographic structure and migration between countries, khat chewing is of increasing significance as it may contribute to the etiology of squamous cell carcinoma in developed countries.
Adekunmi Fasanmade; Evelyn Kwok; Laurence Newman
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-05-07
Journal Detail:
Title:  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics     Volume:  104     ISSN:  1528-395X     ISO Abbreviation:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-06-19     Completed Date:  2007-07-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508562     Medline TA:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e53-5     Citation Subset:  D; IM    
Maxillofacial Unit, University College London Hospitals Foundation Trust, London, England, UK.
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MeSH Terms
Carcinoma, Squamous Cell / chemically induced*
Catha / adverse effects*
Mouth Floor / pathology,  surgery
Mouth Neoplasms / chemically induced*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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