Document Detail


Oral rehydration in hypernatremic and hyponatremic diarrheal dehydration.
MedLine Citation:
PMID:  6869329     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ninety-four well-nourished, bottle-fed infants with hypernatremic (N = 61) or hyponatremic (N = 33) diarrheal dehydration were treated with oral rehydration. In 61 hypernatremic and 25 hyponatremic infants, two thirds of the fluid volume were given as glucose/electrolyte solution containing 90 mmole of sodium per liter and one third as plain water; the other eight hyponatremic infants were given glucose/electrolyte solution alone. Fluid deficits were successfully and rapidly replaced with oral therapy alone in all 61 hypernatremic infants (mean +/- SEM, 8.5 +/- 0.6 hours) and in 31 of those with hyponatremia (mean +/- SEM, 10 +/- 1.2 hours). Two hypernatremic infants required some intravenous (IV) fluids. The mean serum sodium levels fell in the hypernatremic infants to normal and rose in those with hyponatremia. Only five (8%) of the 61 hypernatremic infants manifested convulsions during oral rehydration; this compared favorably with the 14% rate of convulsions encountered previously when we used IV rehydration.
Authors:
D Pizarro; G Posada; N Villavicencio; E Mohs; M M Levine
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of diseases of children (1960)     Volume:  137     ISSN:  0002-922X     ISO Abbreviation:  Am. J. Dis. Child.     Publication Date:  1983 Aug 
Date Detail:
Created Date:  1983-08-26     Completed Date:  1983-08-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370471     Medline TA:  Am J Dis Child     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  730-4     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Dehydration / etiology,  therapy*
Diarrhea, Infantile / complications*
Electrolytes / therapeutic use
Fluid Therapy*
Glucose / therapeutic use
Humans
Hypernatremia / etiology,  therapy*
Hyponatremia / etiology,  therapy*
Infant
Infant, Newborn
Chemical
Reg. No./Substance:
0/Electrolytes; 50-99-7/Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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