Document Detail


Oral photochemotherapy in lichen planus (LP) and mycosis fungoides (MF): ultrastructural modifications of the infiltrating cells.
MedLine Citation:
PMID:  87077     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Six patients (5 with mycosis fungoides and 1 with lichen planus) treated with PUVA, were subjected to biopsy of lesional skin before and during oral photochemotherapy. Ultrastructurally, a reduction in the density of cellular infiltrate was observed in the superficial dermis. In the same areas, necrotic cellular changes were observed. PUVA therapy exercises its beneficial effect by direct destruction of these cells.
Authors:
J P Ortonne; D Schmitt; A Alario; J Thivolet
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta dermato-venereologica     Volume:  59     ISSN:  0001-5555     ISO Abbreviation:  Acta Derm. Venereol.     Publication Date:  1979  
Date Detail:
Created Date:  1979-07-25     Completed Date:  1979-07-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370310     Medline TA:  Acta Derm Venereol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  211-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Cell Nucleus / ultrastructure
Cytoplasm / ultrastructure
Humans
Lichen Planus / drug therapy*,  pathology
Methoxsalen / therapeutic use*
Mycosis Fungoides / drug therapy*,  ultrastructure
Necrosis
Photochemotherapy*
Skin / ultrastructure*
Skin Neoplasms / drug therapy*,  ultrastructure
Ultraviolet Therapy
Chemical
Reg. No./Substance:
298-81-7/Methoxsalen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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