Document Detail

Oral misoprostol use in early complicated pregnancy.
MedLine Citation:
PMID:  8863909     Owner:  NLM     Status:  MEDLINE    
Eighty-four patients with early complicated pregnancies such as intrauterine death, blighted ovum pregnancy and missed abortion were treated with oral misoprostol. If abortion did not occur, 200 micrograms misoprostol was given once an hour, with an average dose of 1000 micrograms (min 200 micrograms, max 1200 micrograms). Complete or partial abortion took place within 7.0 +/- 5.1 h in 92.5% of patients. Of the patients, 11.9% and 83.3% had complete and partial abortion, respectively, without major complications. We observed only minor side-effects such as nausea, vomiting, diarrhea, hypotension, fever, headache and abdominal pain. This study demonstrates that the use of oral misoprostol is a simple, inexpensive and easy procedure for terminating early complicated pregnancies, although additional surgical evacuation of the uterus was required in the large majority of patients.
A Haberal; H Celikkanat; S Batioglu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in contraception : the official journal of the Society for the Advancement of Contraception     Volume:  12     ISSN:  0267-4874     ISO Abbreviation:  Adv Contracept     Publication Date:  1996 Jun 
Date Detail:
Created Date:  1997-01-14     Completed Date:  1997-01-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8607435     Medline TA:  Adv Contracept     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  139-43     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, Social Security Association Hospital, Ankara, Turkey.
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MeSH Terms
Abortifacient Agents, Nonsteroidal* / administration & dosage,  adverse effects
Abortion, Therapeutic*
Administration, Oral
Gestational Age
Misoprostol* / administration & dosage,  adverse effects
Pregnancy Complications*
Treatment Outcome
Reg. No./Substance:
0/Abortifacient Agents, Nonsteroidal; 59122-46-2/Misoprostol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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