| Oral misoprostol for induction of labour. | |
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MedLine Citation:
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PMID: 20378037 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the effect of oral Misoprostol in labour induction with respect to ease of administration and induction-to-delivery time interval. STUDY DESIGN: Observational study. PLACE AND DURATION OF STUDY: Gynaecology/Obstetrics Department, Holy Family Hospital, Rawalpindi, from March to August 2006. METHODOLOGY: Women with live singleton pregnancy of > 37 weeks gestation with cephalic presentation, with an indication for induction of labour were inducted. Oral misoprostol 50 microg to 400 microg was given in divided doses at 4 hours interval upto a maximum of 4 doses, till labour was induced. Fetomaternal outcome and induction to delivering time interval in hours was noted. RESULTS: In 6 months duration, 250 mothers were recruited for the study. The main indication for labour induction was post date pregnancy (52%) and oxytocin was given in 50% cases. The majority (96%) of mothers went into labour but 4% (9) had failed induction. The majority (73%, n=176/241) of mothers delivered vaginally, 99% being delivered in the first 24 hours. Mean induction-delivery interval was 11+/-2.7 hours. Sixty five (27%) had to undergo emergency lower segment caesarean section, the major indication being fetal distress (41.5%, n=27) and meconium staining of liquor (40%, n=26). Again, a majority (95%) of the babies were delivered with good Apgar score. However, 10.8% developed meconium aspiration syndrome. Early neonatal deaths occurred in 0.8% (2) cases. Maternal hyper stimulation was seen in 1 case (0.4%). CONCLUSION: Oral misoprostol as an agent for labour induction in term pregnancy was easy to administer and the majority of women (99%) delivered in the first 24 hours. |
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Authors:
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Shazia Syed; Rizwana Chaudhri; Farwa Rizvi; Muhammad Afzal |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP Volume: 20 ISSN: 1022-386X ISO Abbreviation: J Coll Physicians Surg Pak Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-04-09 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9606447 Medline TA: J Coll Physicians Surg Pak Country: Pakistan |
Other Details:
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Languages: eng Pagination: 102-5 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynaecology, Holy Family Hospital, Rawalpindi. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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