| Oral microbiota associated with hyposalivation of different origins. | |
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MedLine Citation:
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PMID: 12588452 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We analysed and compared the oral microbial flora in four groups with hyposalivation caused by radiation therapy (RT), primary Sjögren's syndrome (pSS), medication or unknown factors (Unknown), or neuroleptic treatment (Neuro). A control group with normal salivary secretion was also included. The subjects included were 54 +/- 8 years old and had 25 +/- 4 teeth. We analysed their microflora in rinsing samples using a cultivation technique. A marked increase in Lactobacillus spp. and Candida albicans was characteristic of the RT group. In the pSS group, 85% of subjects had high numbers of mutans streptococci despite good oral hygiene, frequent dental visits and fluoride use. The Unknown group had an oral flora similar to that of the controls. In the Neuro group, with a stimulated secretion rate similar to that of the Unknown group, the numbers of aciduric and acidogenic microorganisms were close to those in the pSS group. The results indicate that changes in the oral microflora associated with hyposalivation are related to the reason for the hyposalivation rather than to the magnitude of the decrease in the salivary secretion rate. |
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Authors:
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A AlmståhI; M Wikström; I Stenberg; A Jakobsson; B Fagerberg-Mohlin |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Oral microbiology and immunology Volume: 18 ISSN: 0902-0055 ISO Abbreviation: Oral Microbiol. Immunol. Publication Date: 2003 Feb |
Date Detail:
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Created Date: 2003-02-17 Completed Date: 2003-05-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8707451 Medline TA: Oral Microbiol Immunol Country: Denmark |
Other Details:
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Languages: eng Pagination: 1-8 Citation Subset: D |
Affiliation:
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Department of Oral Microbiology, Institute of Odontology, Hospital Dental Clinic, Vasa Hospital, Göteborg, Sweden. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Analysis of Variance Antipsychotic Agents / adverse effects Candida albicans / isolation & purification Colony Count, Microbial Cranial Irradiation / adverse effects Female Humans Lactobacillus / isolation & purification Male Middle Aged Sjogren's Syndrome / complications Statistics, Nonparametric Streptococcus mutans / isolation & purification Xerostomia / etiology, microbiology* |
| Chemical | |
Reg. No./Substance:
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0/Antipsychotic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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