Document Detail

Oral microbial colonization in patients with systemic lupus erythematous: correlation with treatment and disease activity.
MedLine Citation:
PMID:  22453994     Owner:  NLM     Status:  Publisher    
Treating patients with systemic lupus erythematosus (SLE) with steroids and immunosuppressive drugs may interfere in the presence of potentially opportunistic microorganisms in the oral cavity. The aim of this study was to evaluate the presence of Candida spp., Staphylococcus spp., Enterobacteria and Pseudomonas spp. in the oral cavity of SLE patients, compared with healthy controls. A group of 40 patients who had received therapy for at least 60 days was selected (19-53 years). For the control group, 40 healthy individuals matched for age, gender and use of partial prosthesis were selected. Oral rinse samples were collected and plated on specific culture media. After incubation, the number of colony forming units (CFU) was obtained and the isolates were identified at species level. Microbial counts were compared between SLE and control by analysis of variance (ANOVA) and Mann-Whitney (p < 0.05 significant). Microorganism counts in patients with and without immunosuppressive drugs, as well with active and inactive disease (according to SLEDAI score) were also compared. No significant differences in CFU/mL between SLE and control patients were observed (yeasts, p = 0.55; Staphylococci, p = 0.24; Enterobacteria/Pseudomonas spp., p = 0.26). No differences in microbial counts were observed regarding clinical parameters tested. The most frequent species isolated in the SLE group were Candida albicans, Staphylococcus epidermidis and Klebsiella oxytoca. In conclusion, no differences in frequency and microorganism levels were found between SLE patients and healthy individuals.
E A F de Araújo Navas; E I Sato; D F A Pereira; G N Back-Brito; J A Ishikawa; A O C Jorge; F L Brighenti; C Y Koga-Ito
Related Documents :
1062974 - Teeth and infective endocarditis.
10753694 - Oral health of patients scheduled for elective abdominal aortic correction with prosthe...
8047494 - Spectrum of infective endocarditis during infancy and childhood: 20-year review.
11139944 - Mitral regurgitation protects from left atrial thrombogenesis in patients with mitral v...
12888044 - Lichen planus and cicatrizing conjunctivitis: characterization of five cases.
3400904 - Cardiac arrest associated with halothane anesthesia in a patient receiving theophylline.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-27
Journal Detail:
Title:  Lupus     Volume:  -     ISSN:  1477-0962     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204265     Medline TA:  Lupus     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Laboratory of Microbiology, Department of Oral Biosciences and Diagnosis, São José dos Campos Dental School, Univ. Estadual Paulista (UNESP), Brazil.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Comparative analysis of the orientation of transmembrane peptides using solid-state (2)H- and (15)N-...
Next Document:  Accuracy of Urea Breath Test Performed Immediately After Emergency Endoscopy in Peptic Ulcer Bleedin...