Document Detail


Oral melanoacanthoma and oral melanotic macule: a report of 8 cases, review of the literature, and immunohistochemical analysis.
MedLine Citation:
PMID:  17767102     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Oral melanoacanthoma (MA) is a rare, benign pigmented lesion, similar to cutaneous MA, characterized by hyperplasia of spinous keratinocytes and dendritic melanocytes. The pathogenesis of oral MA remains uncertain, although its clinical behavior is suggestive of a reactive origin. The most common intraoral sites are the buccal mucosa, lip, palate and gingiva. The average age of presentation is 28 years, mainly in blacks, with a strong female predilection. The oral melanotic macule (MM) is a small, well-circumscribed brown-to-black macule that occurs on the lips and mucous membranes. The etiology is not clear and it may represent a physiologic or reactive process. The average age of presentation is 43 years, with a female predilection. A biopsy is recommended to distinguish these lesions from each other and from other oral melanocytic lesions. We depict four cases each of oral MA and MM, affecting Caucasian and Latin American mestizo patients. The clinicopathological features of these cases reflect its ample spectrum, and to the best of our knowledge, it is the first example of oral MA affecting a Caucasian boy reported in the English literature. Therefore oral MA and MM should be considered in the differential diagnosis of pigmented lesions in the oral mucosa in these populations.
Authors:
Román Carlos-Bregni; Elisa Contreras; Ana Carolina Netto; Adalberto Mosqueda-Taylor; Pablo Agustin Vargas; Jacks Jorge; Jorge Esquiche León; Oslei Paes de Almeida
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2007-09-01
Journal Detail:
Title:  Medicina oral, patología oral y cirugía bucal     Volume:  12     ISSN:  1698-6946     ISO Abbreviation:  Med Oral Patol Oral Cir Bucal     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-09-03     Completed Date:  2007-10-03     Revised Date:  2009-12-11    
Medline Journal Info:
Nlm Unique ID:  101231694     Medline TA:  Med Oral Patol Oral Cir Bucal     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  E374-9     Citation Subset:  D; IM    
Affiliation:
Departamento de Patología y Medicina Oral, Centro Clínico de Cabeza y Cuello, Guatemala. roman@guate.net.gt
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MeSH Terms
Descriptor/Qualifier:
Acanthoma / complications,  pathology*
Adult
Child
Female
Humans
Immunohistochemistry
Male
Melanosis / complications,  pathology*
Mouth Diseases / complications,  pathology*
Mouth Neoplasms / complications,  pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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