Document Detail


Oral manifestations of patients with Marfan syndrome: a case-control study.
MedLine Citation:
PMID:  12075206     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The purpose of this study was to conduct a complete analysis of the oral abnormalities of patients with Marfan syndrome. STUDY DESIGN: Twenty three patients with Marfan syndrome and 69 healthy controls were studied. The subjects were screened for cariologic and periodontal alterations, as well as structural defects of enamel and dentin. Data analysis was performed by using the t test, the chi-square test, and regression models. RESULTS: Patients aged 0 to 17 years were significantly at risk for caries. Local hypoplastic enamel spots were more frequent in Marfan syndrome and could be related to caries history of the deciduous dentition. Root deformity, abnormal pulp shape, and pulpal inclusions were a frequent finding in patients with Marfan syndrome. Calculus and gingival indices were significantly higher in the study group as well. CONCLUSIONS: This study shows the importance of early diagnosis of oral anomalies and timely treatment of dental problems in Marfan syndrome. A series of therapeutic guidelines to be integrated in treatment strategies is proposed.
Authors:
P J A De Coster; L C M Martens; A De Paepe
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics     Volume:  93     ISSN:  1079-2104     ISO Abbreviation:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Publication Date:  2002 May 
Date Detail:
Created Date:  2002-06-20     Completed Date:  2002-09-03     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9508562     Medline TA:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  564-72     Citation Subset:  D; IM    
Affiliation:
Ghent University, Ghent, Belgium. peter.decoster@rug.ac.be
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Case-Control Studies
Chi-Square Distribution
Child
Child, Preschool
Cross-Sectional Studies
Dental Calculus / etiology
Dental Caries / etiology
Dental Caries Susceptibility
Dental Enamel / abnormalities
Dental Enamel Hypoplasia / etiology
Dental Pulp / abnormalities
Dentin / abnormalities
Female
Humans
Infant
Male
Marfan Syndrome / complications*
Middle Aged
Periodontal Diseases / etiology
Periodontal Index
Regression Analysis
Risk Factors
Statistics as Topic
Statistics, Nonparametric
Tooth Diseases / etiology*
Tooth Root / abnormalities

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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