| Oral low-dose tacrolimus therapy for refractory hemophagocytic syndrome associated with systemic lupus erythematosus. | |
| | |
MedLine Citation:
|
PMID: 21720923 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Hemophagocytic syndrome (HPS) is an unusual disorder associated with systemic lupus erythematosus (SLE). A 64-year-old woman was admitted because of fever and urticarial vasculitis. Laboratory data revealed pancytopenia and immunological abnormalities, suggesting elevated disease activity. Prednisolone monotherapy failed to improve the pancytopenia despite the amelioration of other clinical findings. Because her condition was suggestive of HPS, tacrolimus at 2-3 mg/day was added to the prednisolone regimen. Eventually, the pancytopenia improved and prednisolone could be effectively tapered. Tacrolimus could be an additional or alternative modality for treating refractory HPS. |
| | |
Authors:
|
Hideyuki Watanabe; Nobuhisa Hirase; Hideaki Goda; Hiroshi Nishikawa; Shoichiro Ikuyama |
Related Documents
:
|
10495233 - Disease-specific outcomes assessment for irritable bowel syndrome. 8280823 - Effect of a 5ht3-antagonist (ondansetron) on rectal sensitivity and compliance in healt... 21798143 - Hypertensive encephalopathy: a rare presentation of williams-beuren syndrome. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-7-1 |
Journal Detail:
|
Title: Modern rheumatology / the Japan Rheumatism Association Volume: - ISSN: 1439-7609 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
|
Created Date: 2011-7-1 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100959226 Medline TA: Mod Rheumatol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Rheumatology, Hematology, and Metabolic Diseases, Kyushu University Hospital at Beppu, 4546 Tsurumibaru, Beppu, Oita, 874-0838, Japan, watanabe@tsurumi.beppu.kyushu-u.ac.jp. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Use of antifungal agents in pediatric and adult high-risk areas.
Next Document: Clostridium difficile Colitis: Factors Associated with Outcome and Assessment of Mortality at a Nati...