| Oral lichenoid lesions, mercury hypersensitivity and combined hypersensitivity to mercury and other metals: histologically-proven reproduction of the reaction by patch testing with metal salts. | |
| | |
MedLine Citation:
|
PMID: 8565487 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We report 11 patients seen between 1991 and 1994 with oral lichenoid lesions (OLL). In 10 cases, there was contact with dental amalgam fillings, and in patient no. 10 with both amalgam restorations and a gold crown. The last patient had, in addition to her OLL, lichen planus of the skin and genital mucosa. In 5 cases, combined sensitization to mercury and other metal salts, particularly gold sodium thiosulfate (GST) and palladium chloride (PDC), was observed. In 10 patients, the lesions considerably improved or totally cleared within 1 to 9 months of replacement of restoration materials. Histological examination of biopsies from the test sites of amalgam, mercuric chloride, GST and PDC, taken 10 or 17 days after application of patch tests, showed lichenoid changes in 7 patients with at least 1 of the allergens. As at least 2 patients had inflammatory lesions of the oral mucosa related to both amalgam and gold restorations, combined sensitization to inorganic and organic mercury derivatives, GST and, in 1 case, PDC, a "dental restoration metal intolerance syndrome" is proposed. |
| | |
Authors:
|
P Koch; F A Bahmer |
Related Documents
:
|
3871737 - Evidence for circulating complexes containing ige in patients with atopic dermatitis. 9146927 - Nasal nitric oxide is increased in allergic rhinitis. 15119017 - The eamg position on the regulation of existing products for treatment with special ref... 2812597 - Preliminary assessment of multidrug therapy in leprosy patients in western samoa. 15220957 - Stem cell transplantation for chronic lymphocytic leukemia: should not more patients ge... 22511937 - Hepatitis c viral evolution in genotype 1 treatment-naïve and treatment-experienced pa... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Contact dermatitis Volume: 33 ISSN: 0105-1873 ISO Abbreviation: Contact Derm. Publication Date: 1995 Nov |
Date Detail:
|
Created Date: 1996-03-06 Completed Date: 1996-03-06 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7604950 Medline TA: Contact Dermatitis Country: DENMARK |
Other Details:
|
Languages: eng Pagination: 323-8 Citation Subset: IM |
Affiliation:
|
Hautklinik der Universität des Saarlandes, Homburg/Saar, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Allergens / adverse effects* Dental Amalgam / adverse effects Dental Restoration, Permanent / adverse effects Dermatitis, Allergic Contact / etiology*, pathology Female Genital Diseases, Female / complications Gold Alloys / adverse effects Gold Sodium Thiosulfate / adverse effects Humans Lichen Planus / complications Lichen Planus, Oral / complications Lichenoid Eruptions / chemically induced*, pathology Male Mercuric Chloride / adverse effects Mercury / adverse effects* Metals / adverse effects* Middle Aged Mouth Diseases / chemically induced*, pathology Palladium / adverse effects Patch Tests |
| Chemical | |
Reg. No./Substance:
|
0/Allergens; 0/Gold Alloys; 0/Metals; 15283-45-1/Gold Sodium Thiosulfate; 7439-97-6/Mercury; 7440-05-3/Palladium; 7487-94-7/Mercuric Chloride; 7647-10-1/palladium chloride; 8049-85-2/Dental Amalgam |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Skin irritation in man: a comparative bioengineering study using improved reflectance spectroscopy.
Next Document: Erythema-multiforme-like eruption due to topical contactants: expression of adhesion molecules and t...