| Oral leukoplakia manifests differently in smokers and non-smokers. | |
| | |
MedLine Citation:
|
PMID: 23019086 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Oral leukoplakias (OL) are potentially malignant lesions that are typically white in color. Smoking is considered a risk factor for developing OL, and dysplastic lesions are more prone to malignant transformation. The aim of this study was to describe the clinical features observed in dysplastic and non-dysplastic OL in both smokers and non-smokers. A total of 315 cases of OL were retrieved and separated into either dysplastic or non-dysplastic lesions, and these cases were further categorized as originating in either smokers or non-smokers. Frequencies of the type of OL lesion, with respect to whether the patients smoked, were established. The results demonstrated that 131 cases of OL were dysplastic (74 smokers and 57 non-smokers), and 184 were non-dysplastic (96 smokers and 88 non-smokers). For OL cases in smokers for which information about alcohol consumption was also available (84 cases), the results revealed no significant difference in the amount of dysplastic and non-dysplastic lesions. Dysplastic lesions were more frequent in male smokers and in non-smoking females. The median age of smokers with cases of OL was significantly lower than in non-smokers; the lowest median ages were observed for female smokers with dysplastic OL. The most frequent anatomical sites of dysplastic lesions were the floor of the mouth in smokers and the tongue in non-smokers. Dysplastic lesions in smokers were significantly smaller than non-dysplastic lesions in non-smokers. Being a male smoker, being female, being younger, and having smaller lesions were associated with dysplastic features in OL. These clinical data may be important for predicting OL malignant transformation. |
| | |
Authors:
|
Joelma Sousa Lima; Décio Dos Santos Pinto Jr; Suzana Orsini Machado de Sousa; Luciana Corrêa |
Related Documents
:
|
3280276 - Primary adenocarcinoma of the ileostomy after colectomy for ulcerative colitis. 6653016 - Gastric gallium-67 uptake in gastritis. 16477336 - Evolution of human herpesvirus type 8-associated gastric kaposi's sarcoma following cor... 23143436 - Retroperitoneal duplication cyst with a fistulous tract to the vagina: a case report. 19281486 - Two cutaneous malignant melanomas at the same anatomic site: a case report with molecul... 19999326 - An unusual cause of pelvic pain: struma ovarii. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-9-27 |
Journal Detail:
|
Title: Brazilian oral research Volume: - ISSN: 1807-3107 ISO Abbreviation: Braz Oral Res Publication Date: 2012 Sep |
Date Detail:
|
Created Date: 2012-9-28 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101307187 Medline TA: Braz Oral Res Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Oral Pathology Department, School of Dentistry, Univ of São Paulo, São Paulo, SP, Brazil. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The effect of a Lucia jig for 30 minutes on neuromuscular re-programming, in normal subjects.
Next Document: CIE L*a*b*: comparison of digital images obtained photographically by manual and automatic modes.