| Oral involvement in mycosis fungoides: report of two cases and a literature review. | |
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MedLine Citation:
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PMID: 11028868 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Oral involvement is uncommon in cutaneous T-cell lymphomas and usually associated with poor prognosis. The clinicopathological and immunohistochemical findings of 2 new cases are described along with a literature review. The first patient had a 10-year history of mycosis fungoides when she developed lesions in the oral tissues. She died 6 months later despite treatment. The immunophenotype was CD3+, CD4+, CD8-, CD30-. The second patient had a mycosis fungoides for 5 years when she developed lesions in the uvula and oropharynx. She was treated with polychemotherapy and she is alive 5 years after oral involvement. The immunophenotype was CD3+, CD4-, CD8+, CD30-. There are conflicting reports about the prognosis in the CD8+ phenotype. The present cases and the literature review seem to indicate that in oral involvement the CD8- phenotype is not associated with a worse prognosis than the CD4+ subtype. However, it is necessary to study new cases to confirm this statement. |
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Authors:
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E G de la Fuente; J L Rodriguez-Peralto; P L Ortiz; N Barrientos; F Vanaclocha; L Iglesias |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Acta dermato-venereologica Volume: 80 ISSN: 0001-5555 ISO Abbreviation: Acta Derm. Venereol. Publication Date: 2000 Jul-Aug |
Date Detail:
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Created Date: 2001-02-05 Completed Date: 2001-02-08 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370310 Medline TA: Acta Derm Venereol Country: NORWAY |
Other Details:
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Languages: eng Pagination: 299-301 Citation Subset: IM |
Affiliation:
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Department of Dermatology, 12 de Octubre University Hospital, Madrid, Spain. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antigens, CD4 / analysis Antigens, CD8 / analysis Female Humans Middle Aged Mouth Neoplasms / pathology, secondary* Mycosis Fungoides / pathology* Oropharyngeal Neoplasms / secondary Skin Neoplasms / pathology* Tongue Neoplasms / secondary Uvula |
| Chemical | |
Reg. No./Substance:
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0/Antigens, CD4; 0/Antigens, CD8 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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