Document Detail

Oral and intralesional steroid therapy in giant cell granuloma.
MedLine Citation:
PMID:  16720455     Owner:  NLM     Status:  MEDLINE    
Giant cell granulomas account for 7% of all benign tumors of the jaw. They are commonly seen as asymptomatic masses. A 4-year-old boy with an exophitic, crusty, hemorrhagic mass on the anterolateral region of the right maxilla was referred to our department. Pathological examination was reported as giant cell granuloma. A mixture of prednisolone, lidocaine and adrenaline was injected intralesionally once a week and oral fluocortone was added to this therapy. A limited surgery could be performed. Intralesional prednisolone and systemic fluocortone therapy seems to be effective, as the lesion stopped growing and increase in bony structures was observed radiologically.
Ela Comert; Mehmet Turanli; Sahin Ulu
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta oto-laryngologica     Volume:  126     ISSN:  0001-6489     ISO Abbreviation:  Acta Otolaryngol.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-05-24     Completed Date:  2007-01-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370354     Medline TA:  Acta Otolaryngol     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  664-6     Citation Subset:  IM    
Otorhinolaryngology Clinic, Ankara Oncology Education and Research Hospital, Ankara, Turkey.
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MeSH Terms
Administration, Oral
Child, Preschool
Combined Modality Therapy
Dose-Response Relationship, Drug
Drug Therapy, Combination
Epinephrine / administration & dosage
Fluocortolone / administration & dosage*
Follow-Up Studies
Granuloma, Giant Cell / drug therapy*,  surgery
Injections, Intralesional
Lidocaine / administration & dosage
Maxillary Diseases / drug therapy*,  surgery
Prednisolone / administration & dosage*
Reg. No./Substance:
137-58-6/Lidocaine; 152-97-6/Fluocortolone; 50-24-8/Prednisolone; 51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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