| Oral ibopamine substitution in patients with intravenous dopamine dependence. | |
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MedLine Citation:
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PMID: 7585741 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a prospective open study we evaluated whether intravenous dopamine infusions can be safely switched to enterally administered ibopamine in dopamine-dependent patients. Six patients defined as being clinically stable, normovolaemic, but dopamine dependent, i.e. with repeated inability to stop intravenous dopamine, were included. Ibopamine was administered via a nasogastric or nasoduodenal tube. During the initial 48-hour period of ibopamine administration the dopamine infusion was gradually decreased and then discontinued. Arterial blood pressure was continuously recorded via a 20-gauge cannula in the radial artery. Urine output was measured each hour. In all 6 patients it was possible to decrease and then discontinue the dopamine infusion whilst maintaining haemodynamic stability and an appropriate diuresis. It was then possible to discharge the patients from the intensive care unit. Normovolaemic, clinically stable but dopamine-dependent patients may be weaned off intravenous dopamine by substitution of enterally administered ibopamine, allowing discharge from the intensive care unit. |
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Authors:
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A R Girbes; A R Milner; B V McCloskey; J H Zwaveling; D J van Veldhuisen; J G Zijlstra; K I Lie |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Cardiology Volume: 86 ISSN: 0008-6312 ISO Abbreviation: Cardiology Publication Date: 1995 |
Date Detail:
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Created Date: 1995-11-30 Completed Date: 1995-11-30 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 1266406 Medline TA: Cardiology Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 391-5 Citation Subset: IM |
Affiliation:
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Department of Surgery, University Hospital Groningen, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Aged Aged, 80 and over Deoxyepinephrine / administration & dosage, analogs & derivatives* Dopamine / administration & dosage* Dopamine Agonists / administration & dosage* Female Humans Infusions, Intravenous Intensive Care* Male Middle Aged Prospective Studies |
| Chemical | |
Reg. No./Substance:
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0/Dopamine Agonists; 501-15-5/Deoxyepinephrine; 66195-31-1/ibopamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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