Document Detail


Oral-facial-digital syndrome with fibular aplasia: a new variant.
MedLine Citation:
PMID:  8261648     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The oral-facial-digital (OFD) syndromes constitute a heterogeneous group of entities usually associated with certain features that permit a specific diagnosis. This report refers to a 10-month-old girl with cleft palate, mesomelic limb shortening, oligopolydactyly, and fibular aplasia. Since this combination has not been described previously, it is proposed as a distinct type of oral-facial-digital syndrome, and we suggest mutations of homeotic genes to explain some abnormalities present in the OFD syndromes.
Authors:
L E Figuera; F Rivas; J M Cantú
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical genetics     Volume:  44     ISSN:  0009-9163     ISO Abbreviation:  Clin. Genet.     Publication Date:  1993 Oct 
Date Detail:
Created Date:  1994-01-27     Completed Date:  1994-01-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0253664     Medline TA:  Clin Genet     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  190-2     Citation Subset:  IM    
Affiliation:
División de Genética, CMNO-IMSS, Guadalajara, Jalisco, Mexico.
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MeSH Terms
Descriptor/Qualifier:
Female
Humans
Infant
Orofaciodigital Syndromes / pathology*
Phenotype

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