Document Detail

Oral doxycycline, niacinamide and prednisolone used to treat bilateral nodular granulomatous conjunctivitis of the third eyelid in an Australian Kelpie dog.
MedLine Citation:
PMID:  16178846     Owner:  NLM     Status:  MEDLINE    
A 5-year-old, female neutered, Australian Kelpie presented with a 2-month history of dramatic bilateral erythematous thickening of the third eyelids. Ophthalmic examination demonstrated raised, pink to red, irregular thickening of the entire palpebral surface of both third eyelids. There were no other ocular abnormalities. A surgical biopsy was taken from each third eyelid. Histopathologic examination revealed sheets of macrophages, plasma cells, lymphocytes, and occasional fibroblasts and neutrophils infiltrating the third eyelid stroma. A diagnosis of chronic granulomatous conjunctivitis was made. Grossly and histopathologically this case closely resembles previously described cases of nodular granulomatous conjunctivitis involving the third eyelids of Collie dogs. This report describes an unusual case of nodular granulomatous conjunctivitis isolated to the third eyelids in an Australian Kelpie. Resolution of the condition was achieved with a combination of oral doxycycline, niacinamide and prednisolone.
Simon Hurn; Christina Mc Cowan; Andrew Turner
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Veterinary ophthalmology     Volume:  8     ISSN:  1463-5216     ISO Abbreviation:  Vet Ophthalmol     Publication Date:    2005 Sep-Oct
Date Detail:
Created Date:  2005-09-23     Completed Date:  2006-01-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100887377     Medline TA:  Vet Ophthalmol     Country:  England    
Other Details:
Languages:  eng     Pagination:  349-52     Citation Subset:  IM    
9 Hamilton Street, Yarraville, Victoria, Australia.
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MeSH Terms
Administration, Oral
Anti-Bacterial Agents / therapeutic use
Anti-Inflammatory Agents / therapeutic use
Chronic Disease
Conjunctivitis / drug therapy,  pathology,  veterinary*
Dog Diseases / drug therapy*,  pathology
Doxycycline / therapeutic use
Drug Therapy, Combination
Granuloma / drug therapy,  pathology,  veterinary*
Niacinamide / therapeutic use
Nictitating Membrane* / pathology
Prednisolone / therapeutic use
Treatment Outcome
Vitamin B Complex / therapeutic use
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Anti-Inflammatory Agents; 12001-76-2/Vitamin B Complex; 50-24-8/Prednisolone; 564-25-0/Doxycycline; 98-92-0/Niacinamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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