Document Detail


Oral desensitization for food hypersensitivity.
MedLine Citation:
PMID:  21530825     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Food allergy has become an increasingly prevalent international health problem. Allergic reactions can result in life-threatening anaphylaxis in a short period of time, so the current standard of care dictates strict avoidance of suspected trigger foods and accessibility to injectable epinephrine. Intervention at the time of exposure is considered a rescue therapy rather than a disease-modifying treatment. Investigators have been studying allergen immunotherapy to promote induction of oral tolerance. This article examines the mechanisms of oral tolerance and the breakdown that leads to food allergy, as well as the history and current state of oral and sublingual immunotherapy development.
Authors:
Michael H Land; Edwin H Kim; A Wesley Burks
Related Documents :
23834595 - Towards metabolic robotics: insights from modeling embodied cognition in a biomechatron...
23724365 - Ecology of an endemic primate species (macaca siberu) on siberut island, indonesia.
24080235 - Hypothesis of homeothermy evolution on isolated south china craton that moved from equa...
23935635 - Specific oral tolerance induction using ifn-gamma in 2 cases of food-dependent exercise...
25461065 - Study on polychlorobiphenyl serum levels in french consumers of freshwater fish.
3394835 - Group housing accelerates growth and induces obesity in adult hamsters.
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Immunology and allergy clinics of North America     Volume:  31     ISSN:  1557-8607     ISO Abbreviation:  Immunol Allergy Clin North Am     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-05-02     Completed Date:  2011-08-02     Revised Date:  2014-09-22    
Medline Journal Info:
Nlm Unique ID:  8805635     Medline TA:  Immunol Allergy Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  367-76, xi     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Desensitization, Immunologic*
Food Hypersensitivity / immunology,  therapy*
Gastrointestinal Tract / immunology
Humans
Immune Tolerance / immunology
Mouth Mucosa / immunology
Treatment Outcome
Grant Support
ID/Acronym/Agency:
5T32-AI007062-32/AI/NIAID NIH HHS; T32 AI007062/AI/NIAID NIH HHS; T32 AI007062-32/AI/NIAID NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Future forms of immunotherapy and immunomodulators in allergic disease.
Next Document:  Peptide and recombinant immunotherapy.