Document Detail

Oral contraceptives and myocardial infarction.
MedLine Citation:
PMID:  4726137     Owner:  NLM     Status:  MEDLINE    
Between January 1970 and December 1972 22 women aged between 31 and 45 years were admitted to the coronary care unit with acute myocardial infarction and six of these (27%) had been taking oral contraceptives. There were nine women aged 40 or less and five of them (55%) had been on oral contraceptives while three of the other four had been sterilized by tubal interruption.Both these figures of prevalence of oral contraceptive use are significantly greater than estimates for the general population of women of similar age. For those aged 30-44 years, current estimates suggest that it is between 8 and 11%.All the women in this study had risk factors recognized as being associated with the premature development of ischaemic heart disease, and the prevalence of these risk factors was similar in those taking oral contraceptives as in those not doing so. Oral contraceptives probably enhance the chance of developing myocardial infarction in women whose risk is increased for other reasons.
D J Radford; M F Oliver
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal     Volume:  3     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1973 Aug 
Date Detail:
Created Date:  1973-10-26     Completed Date:  1973-10-26     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  428-30     Citation Subset:  AIM; IM    
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MeSH Terms
Acute Disease
Contraceptives, Oral / adverse effects*
Coronary Disease / genetics
Glucose Tolerance Test
Hypercholesterolemia / complications
Hypertension / complications
Middle Aged
Myocardial Infarction / chemically induced*
Obesity / complications
Smoking / complications
Sterilization, Tubal
Reg. No./Substance:
0/Contraceptives, Oral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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